MSAT - Process Analytical Technology Scientist

Our client belongs to the food production industry who is cultivating the future of sustainable seafood by crafting delicious, nutritious, affordable cultivated fish that is better for the health, the oceans, and our planet. They are weaving together the deep wisdom of the oceans with modern innovation to develop reasonable and healthy seafood that provides a sustainable alternative to the harmful impact of traditional fishing practices.

Responsibilities:

• Aiding in setup and monitoring of bioprocess from 10L to 1000L bioreactors, especially operating associated sensors and analytical instruments.
• Acting as internal subject matter expert on all PAT instruments and associated data management pipelines.
• Leveraging process analytical data to identify opportunities for process optimization and improved control.
• Evaluation and selection of PAT equipment for streamlined process development and production.
• Collaboration with R&D, production and engineering teams to support day-to-day operations, product development, and regulatory needs.
• Lead investigations by analysing the data to identify anomalies, investigate their causes, and propose solutions.
• Understand the integration of PAT equipment requirements with electronic batch records to ensure all compliance and data monitoring needs are captured in manufacturing electronic documentation.
• Support other core PAT activities (e.g. preventative maintenance planning, system upgrades, periodic review, change management, deviation management, external agency/internal inspections).

Requirements:

• 3-5 years experience with animal cell culture in production reactors of at least 1 kL
• Experience with scaling animal cell processes from bench to production (10 to 1kL+ range), especially in PAT-led approaches for rapid, efficient scale-up
• Proven experience independently designing and troubleshooting fermentation experiments using PAT approaches and instruments.

Education:

• PhD. in Chemical Engineering, Biotechnology or related field + 5 years or M.S + 7 years of relevant industrial hands-on experience

Skills:

• Hands-on experience with PAT instruments and integration of sensors with bioreactor operations and control software is essential.
• In-depth knowledge of operation and optimization of in-line optical sensors, especially IR, for online monitoring and process control.
• Capable of working within a diverse team of internal and external stakeholders
• Strong spoken and written English language skills.